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Inserted and Modified Residues in Protein Structures: A Database (IMRPS) |
About:
IMRPS is a database for Inserted and Modified Residues in macromolecular structures available in the Protein Data Bank (PDB). Modified residues present in proteins are the result of post translational modifications (PTMs). These PTMs increase the functional diversity of the proteome and influence various biological processes and diseased conditions. Therefore, identifying and understanding of PTMs in various protein structures is of great significance. In view of this, an online database, Inserted and Modified Residues in Protein Structure (IMRPS) has been developed. IMRPS is a derived database that furnishes information on the residues modified and inserted in the protein structures, available in the Protein Data Bank (PDB). The database is equipped with a graphical user interface and has an option to view the data for non-redundant protein structures (25% and 90%) as well. A quality criteria cut-off has been incorporated to assist in displaying the specific set of PDB-ids. The entire protein structure along with the inserted or modified residues can be visualized in JSmol. The source code can be accessed at https://github.com/darshanrsm1/IMRPS.
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